Figure 3.

VCX is expressed in a subset of breast cancer and melanoma tumors and correlates with the expression of other VCX family members. (A) RNA expression of VCX family members in normal breast and breast cancer tissues. Data were generated using RNA sequencing data from the TCGA repository. Results are presented as relative expression levels (normalized number of reads). (B) Expression of VCX family members and GAGE, MAGE-A1, and CTAG1B (NY-ESO-1) CT antigens primary and metastatic melanoma tumors. Data were generated using RNA sequencing data from the TCGA repository. Results are presented as relative expression levels (normalized number of reads). (C) Spearman correlation between expression of VCX2 and other members of the VCX family in primary (blue) and metastatic (red) melanoma tumors. VCX significantly correlated with all other VCX genes. The p-values were calculated using the (unpaired) Mann-Whitney U test.