Table 1. Summary of the coronavirus disease 2019 vaccines introduced in the Republic of Korea.
Manufacturer | Platform | Doses | Progress | Time of introduction in Korea4 | Contracted doses | Overall Efficacy | Efficacy in United Kingdom (B.1.1.7 as dominant variant) | Efficacy in South Africa (B.1.351 as dominant variant) |
---|---|---|---|---|---|---|---|---|
Pfizer/BioNtech | mRNA | 2 | Currently in use | February 2021 (COVAX facility) | 20 million doses (for 10 million people) | 95%5 | No biologically significant difference from previous variants9 | Not available |
3rd quarter of 2021 (government contract) | ||||||||
Moderna | mRNA | 2 | Currently in use | 2nd quarter of 2021 | 40 million doses (for 20 million people) | 94%6 | No significant impact of neutralizing titers against B.1.1.710 | 6-fold reduction in neutralizing titers was observed against the B.1.351 variant10 |
Astra Zeneca | Adenovirus-vector | 2 | Currently in use | February 2021 | 20 million doses (for 10 million people) | 62%a11 | 74.6%13 | Limited efficacy against mild disease14 |
82%b12 | ||||||||
JNJ | Adenovirus-vector | 1 | Phase 3 clinical trial completed (interim) | 2nd quarter of 2021 | 6 million doses (for 6 million people) | 66%c7 | 86%d | 57% |
Novavax | Protein subunit | 2 | Phase 3 clinical trial completed (interim) | Contract in progress | 40 million doses (for 20 million people) | 89%8 | 89% | 60% (HIV-negative population) |
49% (including HIV-positive population) |
HIV = human immunodeficiency virus.
aWith standard dose; bA longer prime-boost interval; cFor moderate to severe disease prevention; dPost-hoc analysis in the United States.