Table 4.
Laboratory findings of critical COVID-19 patients on admission.
| Reference values | Corticosteroid treatment | Non-corticosteroid treatment | P-value | |
|---|---|---|---|---|
| (n = 68) | (n = 28) | |||
| White blood cell count (×109/L) | 4.00–10.00 | 7.79 (5.12–10.95) | 7.94 (5.29–11.93) | 0.763 |
| Lymphocyte count (×109/L) | 1.50–4.00 | 0.81 (0.61–1.13) | 1.01 (0.75–1.59) | 0.551 |
| Neutrophil count (×109/L) | 2.00–7.00 | 6.25 (3.55–8.88) | 5.72 (3.31–8.99) | 0.856 |
| NLR | 0.78–3.53 | 7.05 (4.26–11.71) | 3.93 (2.22–9.87) | 0.856 |
| Monocyte count (×109/L) | 0.12–1.00 | 0.35 (0.21–0.53) | 0.45 (0.26–0.73) | 0.551 |
| Platelet count (×109/L) | 99.00–303.00 | 187.00 (157.75–257.00) | 244.00 (167.75–285.75) | 0.763 |
| APTT(s) | 21.00–37.00 | 29.13 (24.33–35.63) | 34.64 (27.50–37.45) | 0.551 |
| fibrinogen (g/L) | 2.00–4.00 | 3.46 (2.76–4.47) | 3.38 (2.32–4.84) | 0.856 |
| D-dimer (μg/ml) | 0.00–0.55 | 0.57 (0.36–1.15) | 0.55 (0.34–1.26) | 0.856 |
| Procalcitonin (ng/ml) | 0.00–0.50 | 0.26 (0.15–0.44) | 0.35 (0.23–0.42) | 0.881 |
| CRP(mg/L) | 0.00–10.00 | 24.45 (9.78–100.19) | 27.70 (8.97–70.47) | 0.763 |
| ESR (mm/1 h) | 0.00–30.00 | 36.00 (26.15–66.50) | 32.00 (26.00–49.00) | 0.763 |
| Creatine kinase (U/L) | 25.00–200.00 | 150.00 (64.00–175.50) | 166.50 (85.90–408.75) | 0.551 |
| Lactate dehydrogenase (U/L) | 91.00–230.00 | 230.00 (171.15–350.40) | 234.40 (191.00–323.50) | 0.856 |
| Creatinine (μmol/L) | 44.00–112.00 | 82.50 (67.50–107.00) | 78.70 (61.90–110.40) | 0.763 |
| BUN (mmol/L) | 2.50–7.10 | 6.57 (4.80–11.03) | 6.52 (5.41–7.50) | 0.856 |
| AST (U/L) | 0.00–40.00 | 37.35 (27.00–55.75) | 50.45 (32.75–66.50) | 0.856 |
| ALT (U/L) | 0.00–50.00 | 42.50 (28.00–63.60) | 37.00 (29.25–55.53) | 0.763 |
| Total bilirubin (μmol/L) | 3.00–21.00 | 20.55 (14.10–28.65) | 17.85 (14.97–24.98) | 0.763 |
Data are median (IQR). P-values comparing corticosteroid treatment and non-corticosteroid treatment are from Mann-Whitney U test or Student's t test, as appropriate, and adjusted for multiple comparisons by FDR method. NLR, neutrophil-to-lymphocyte ratio; APTT, activated partial thromboplastin time; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; BUN, blood urea nitrogen; AST, aspartate transaminase; ALT, alanine aminotransferase.