Table 5.
Laboratory findings of critical COVID-19 patients before discharge.
| Reference values | Corticosteroid treatment | Non-corticosteroid treatment | P-value | |
|---|---|---|---|---|
| (n = 68) | (n = 28) | |||
| White blood cell count (×109/L) | 4.00–10.00 | 8.48 (5.88–12.78) | 6.90 (4.32–8.46) | 0.015 |
| Lymphocyte count (×109/L) | 1.50–4.00 | 0.75 (0.54–1.12) | 0.86 (0.52–1.33) | 0.475 |
| Neutrophil count (×109/L) | 2.00–7.00 | 6.44 (3.90–10.83) | 5.19 (2.75–7.29) | 0.015 |
| NLR | 0.78–3.53 | 9.57 (4.70–16.21) | 6.12 (2.43–9.67) | 0.015 |
| Monocyte count (×109/L) | 0.12–1.00 | 0.45 (0.28–0.65) | 0.48 (0.25–0.66) | 0.692 |
| Platelet count (×109/L) | 99.00–303.00 | 185.00 (125.75–249.75) | 233.00 (128.50–300.50) | 0.100 |
| APTT(s) | 21.00–37.00 | 33.00 (25.75–41.00) | 35.50 (32.10–49.25) | 0.440 |
| fibrinogen (g/L) | 2.00–4.00 | 3.26 (2.03–4.23) | 3.50 (2.13–4.48) | 0.692 |
| D-dimer (μg/ml) | 0.00–0.55 | 1.05 (0.48–6.66) | 0.54 (0.34–2.52) | 0.642 |
| Procalcitonin (ng/ml) | 0.00–0.50 | 0.32 (0.12–0.58) | 0.34 (0.21–0.44) | 0.692 |
| CRP(mg/L) | 0.00–10.00 | 61.70 (24.88–156.85) | 42.41 (15.25–122.63) | 0.475 |
| ESR (mm/1 h) | 0.00–30.00 | 46.00 (32.00–78.50) | 46.00 (31.25–81.75) | 0.719 |
| Creatine kinase (U/L) | 25.00–200.00 | 178.00 (50.93–357.25) | 187.50 (98.80–384.00) | 0.903 |
| Lactate dehydrogenase (U/L) | 91.00–230.00 | 314.00 (214.00–579.00) | 309.00 (210.00–393.00) | 0.692 |
| Creatinine (μmol/L) | 44.00–112.00 | 83.40 (63.90–145.25) | 84.50 (66.13–129.75) | 0.692 |
| BUN (mmol/L) | 2.50–7.10 | 7.80 (5.33–18.85) | 7.60 (4.99–14.47) | 0.692 |
| AST (U/L) | 0.00–40.00 | 64.00 (41.00–112.00) | 62.00 (46.75–78.00) | 0.692 |
| ALT (U/L) | 0.00–50.00 | 67.00 (46.00–133.00) | 61.00 (41.25–114.00) | 0.692 |
| Total bilirubin (μmol/L) | 3.00–21.00 | 28.70 (19.65–34.13) | 22.15 (17.98–30.80) | 0.692 |
| SOFA | 10.50 (5.25–13.00) | 5.00 (4.00–7.00) | 0.015 |
Data are median (IQR). P-values comparing corticosteroid treatment and non-corticosteroid treatment are from Mann-Whitney U test or Student's t test, as appropriate, and adjusted for multiple comparisons by FDR method. NLR, neutrophil-to-lymphocyte ratio; APTT, activated partial thromboplastin time; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; BUN, blood urea nitrogen; AST, aspartate transaminase; ALT, alanine aminotransferase; SOFA, sequential organ failure assessment. The bold P-values indicate P < 0.05.