Table 2.

Functional outcome of SMA patients

Pt No	Age at first LP (month)	Motor functions score*		Motor milestone score†		Respiratory status	Feeding	Adverse reactions	Extra admission (n)	Follow-up duration (month)/Numbers of injection (n)
		Before first dose	Last follow-up	Before first dose	Last follow-up
SMA type 1
1	1.1	8	22	N	Improved head control (wobble) Kicks leg horizontally	NIV <6 h/d	OF	N	-	2.1/4
2	1.4	10	24	N	Voluntary grasp using whole hand	NIV <6 h/d	OF	N	-	2.1/4
3	15.1	4	8	N	Voluntary grasp using whole hand Kicks leg horizontally	24-h IMV	EF	N	3: pneumonia	21.9/9
4	44.7	0	0	N	N	24-h IMV	EF	N	1: febrile illness	22.1/9
SMA type 2
5	46.7	8	12 (12‡)	Sitting without support	Sitting without support	SB	OF	N	-	8.0/6
6	106	10	13 (17‡)	Sitting with support	Sitting without support	SB	OF	N	1: AGE	5.2/4
7	269.4	1	3 (15‡)	Sitting with support	Sitting without support	SB	OF	N	-	6.1/5

*SMA types 1 and 2 patients were assessed using CHOP INTEND score and HFSME, respectively. ^†SMA types 1 and 2 patients were assessed using HINE section 2 and WHO motor milestone, respectively. ^‡RULM score. AGE–acute gastroenteritis; EF–enteral feeding; IMV–invasive mechanical ventilation; N–none; NIV–noninvasive ventilation; OF–oral feeding; SB–spontaneous breathing