Table 4.
Multivariable Cox Regression Analyses for PFS and OS
| Variables | PFS | OS | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| ECOG PS | ||||
| 0–1 | ||||
| 2 | 2.562(1.667–3.940) | <0.001 | 2.431(1.571–3.761) | <0.001 |
| Brain metastasis | ||||
| Yes | 1.630(0.980–2.711) | 0.060 | 1.495(0.886–2.525) | 0.132 |
| No | ||||
| Gender | ||||
| Female | 1.206(0.825–1.761) | 0.333 | ||
| Male | ||||
| NLR | ||||
| ≥3.36 | 1.275 (0.860–1.867) | 0.212 | ||
| <3.36 | ||||
| SIRI | ||||
| ≥0.71 | 2.384(1.275–4.459) | 0.007 | 1.721 (1.024–3.898) | 0.042 |
| <0.71 | ||||
Abbreviations: ECOG PS, Eastern Cooperative Oncology Group performance status; SIRI, systemic immune response index; NLR, neutrophil to lymphocyte ratio; OS, overall survival; PFS, progression-free survival.