The 1st DP time (A) and 1st DPH (B), and FVIII concentration in
Kovaltry® and Jivi® measured with various APTT
reagents. Closed circle, Kovaltry®; open circle,
Jivi®; [FVIII concentrations] 1, 1.00 IU; 2, 0.50 IU; 3, 0.10 IU;
4, 0.05 IU; 5, 0.01 IU; 6, 0.005 IU. [APTT reagents] A, APTT-SP; B, APTT-SS;
C, STA Cephascreen; D, Coagpia APTT-N; E, APTT PSL; F, C.K. Prest; G,
APTT-SLA; H, TC APTT; I, APTT FS; J, APTT FSL; K, PTT ACT; L, STA PTT A.
[Abbreviations] HemosIL APTT-SP; APTT-SP and HemosIL SynthASil; APTT-SS
(Instrumentation Laboratory), STA Cephascreen; STA Cephascreen, D, STA PTT
Automate; STA PTT A and C.K. Prest (Diagnostica Stago S.A.S), Coagpia
APTT-N; APTT-N (SEKISUI MEDICAL CO., LTD.), Thrombocheck APTT-SLA; APTT-SLA
and Thrombocheck APTT; TC APTT (Sysmex Corporation) and Dade®
Actin® FS Activated PTT Reagent; APTT FS, Dade®
Actin ® FSL Activated PTT Reagent; APTT FSL, Dade®
Actin® FSL Activated Cephaloplastin Reagent; APTT ACT and
Pathromtin ® SL; APTT PSL (Siemens Healthcare Diagnostics
Products GmbH). 1stDPT, 1st derivative peak time: FVIII, coagulation factor
FVIII.