Table 2.

Concentrations of FVIII in Jivi^®, as Determined by Clotting (With Various APTT Reagents) and Chromogenic Substrate Methods.

Jivi®		X	Methods	A	B	C	D	E	F	G	H	I	J	K	L
FVIII(IU)	1.00	1.01	APTT	0.22	1.06	0.96	1.01	0.83	0.41	1.08	0.85	0.91	1.10	0.82	0.08
			1st DPT	0.10	1.30	1.10	1.20	0.56	0.54	1.10	0.98	1.10	1.30	1.02	0.08
			1st DPH	0.04	1.88	1.20	1.46	1.24	1.34	1.30	1.26	1.16	1.34	1.70	0.13
	0.50	0.43	APTT	0.09	0.54	0.50	0.51	0.46	0.19	0.54	0.44	0.44	0.50	0.38	0.05
			1st DPT	0.04	0.62	0.56	0.56	0.28	0.26	0.54	0.51	0.56	0.07	0.51	0.04
			1st DPH	0.02	0.92	0.62	0.72	0.64	0.64	0.70	0.62	0.56	0.70	0.88	0.04
	0.10	0.11	APTT	0.02	0.11	0.11	0.10	0.11	0.08	0.11	0.10	0.10	0.10	0.10	0.02
			1st DPT	0.01	0.13	0.11	0.11	0.07	0.09	0.12	0.10	0.13	0.12	0.11	0.01
			1st DPH	0.003	0.18	0.13	0.14	0.18	0.14	0.17	0.16	0.16	0.14	0.16	0.1.2
	0.05	0.04	APTT	0.01	0.05	0.05	0.05	0.05	0.04	0.07	0.05	0.05	0.04	0.05	0.01
			1st DPT	0.002	0.06	0.05	0.05	0.04	0.04	0.05	0.05	0.06	0.06	0.05	0.004
			1st DPH	0.001	0.08	0.06	0.07	0.08	0.08	0.08	0.08	0.07	0.07	0.07	0.06
	0.01	0.007	APTT	0.003	0.01	0.01	0.01	0.01	0.01	0.02	0.01	0.01	0.01	0.01	error
			1st DPT	error	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.001
			1st DPH	error	0.01	0.01	0.01	0.02	0.01	0.02	0.02	0.02	0.02	0.02	0.001
	0.005	0.002	APTT	error	0.005	0.005	0.006	error	error	0.007	0.005	0.005	0.005	0.005	error
			1st DPT	error	0.006	0.005	0.006	error	0.004	0.006	0.005	0.006	0.006	0.005	error
			1st DPH	error	0.006	0.006	0.007	error	0.008	0.007	0.007	0.008	0.007	0.008	error

X, chromogenic substrate method; A, 2ndDPT; B-L, FFT; 1stDPT, first derivative peak time; FVIII, coagulation factor FVIII. 1stDPH, first derivative peak height;

APTT, activated partial thromboplastin time; 2nd DPT, second derivative peak time; [APTT reagents] A, APTT-SP; B, APTT-SS; C, STA Cephascreen; D, Coagpia APTT-N; E, APTT PSL; F, C.K. Prest; G, APTT-SLA; H, TC APTT; I, APTT FS; J, APTT FSL; K, PTT ACT; L, STA PTT A.