Table 1.
Soft Drusen Baseline Characteristics and Growth Rates of Soft Drusen Volume in Area Per Year Including Differences Between Topographic Areas
| ETDRS | Normalized | Covered | Maximum | Volume Growth | Area Growth |
|---|---|---|---|---|---|
| Subfields | Volumenl/mm2 | Area% | Heightµm | Rates nL/mm2/year | Rates%/y |
| Center | 32.9 ± 41.8 | 43 ± 31 | 120.5 ± 54.4 | 9.2 ± 10.6 | 7.0 ± 7.3 |
| Inner ring | 14.4 ± 16.3 | 24 ± 20 | 130.9 ± 51.6 | 3.8 ± 4.0 | 4.0 ± 4.4 |
| Outer ring | 1.7 ± 2.6 | 4 ± 5 | 93.6 ± 39.1 | 0.5 ± 0.9 | 1.0 ± 1.4 |
| Center versus inner ring | P < 0.001 | P < 0.001 | P = 0.084 | P < 0.001 | P = 0.009 |
| Center versus outer ring | P < 0.001 | P < 0.001 | P < 0.001 | P < 0.001 | P < 0.001 |
| Inner versus outer ring | P = 0.002 | P < 0.001 | P < 0.001 | P = 0.004 | P < 0.001 |
| Ratio, center versus outer ring | 24.6 | 10.8 | 1.3 | 19.1 | 7.0 |
| Ratio, center versus inner ring | 2.3 | 1.8 | 0.9 | 2.4 | 1.8 |
| Ratio, inner versus outer rings | 10.6 | 6.0 | 1.4 | 8.0 | 4.0 |
Soft drusen baseline characteristics and growth rates of normalized soft drusen volume and area per year including differences between topographic areas.
Volume of soft drusen was normalized to nanoliter per square millimeter. Area was calculated as percentage of soft drusen coverage in the respective region and maximum height indicated in micrometer (µm). Calculation of growth rate of soft drusen volume indicated in nL/mm2 and area indicated in percentage per year included all data points from follow-up.