The relationships between LLD and structure-function variables such as OCT and microperimetry. (a) Microperimetry mean sensitivity and LLD showing a significant negative Spearman rank correlation for both choroideremia (ρ = −0.59, P < 0.001) and RPGR-associated RP (ρ = −0.83, P < 0.001). (b) Low luminance deficit and microperimetry central 4-point mean sensitivity correlation analysis, showing a significant negative Spearman rank correlation again with both choroideremia (ρ = −0.61, P < 0.001) and RPGR-associated RP (ρ = −0.68, P < 0.001). (c) OCT ellipsoid zone width and LLD correlation, with both data sets showed a significant Spearman rank correlation, choroideremia (ρ = −0.59, P < 0.001) and RPGR-associated RP (ρ = −0.76, P < 0.001). The horizontal blue dashed lines highlight 13 LLD, which is the upper normal limit for controls.