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A schematic representation of PRISM functionalities. PRISM can be run on local computers as well as interactively on the web server. PRISM predictions can be used for multiple purposes. Predicting the interaction between two proteins and PPI networks is possible with PRISM. In addition, with an accurate design of the template set, conformational changes can be handled in the prediction. The effect of residue mutations can be analyzed by comparing the wild-type and mutated predictions
