Table 4.
BRAF and KRAS mutants in 66 colorectal carcinomas
CD274 expression |
||||
---|---|---|---|---|
Total No. 66 (100%) [100%] |
Positive 16 (24%) [100%] |
Negative 50 (76%) [100%] |
P-value | |
Gene mutation | P < 0.001a | |||
BRAF mutant | 19 (100%) [29%] |
14 (74%) [88%] |
5 (25%) [10%] |
|
KRAS mutant | 27 (100%) [41%] |
1 (4%) [6%] |
26 (96%) [52%] |
|
Wild type | 20 (100%) [30%] |
1 (5%) [6%] |
19 (95%) [38%] |
P-value was calculated by the Fisher’s exact test for CD274 expression. The Bonferroni-corrected P-value for significance was P = 0.017(0.05/3). P < 0.001 (BRAF mutant vs KRAS mutant), P < 0.001 (BRAF mutant vs wild type).