Fig. 4.

Setup and real time B-mode images of the channel containing PFP NDs. A) Schematic diagram of the experimental setup employed to investigate the acoustic response of NDs. The suspension of NDs was conveyed through a flow phantom at 0.4 mL/min and exposed to 0.5 MHz ultrasound emitted by a FUS transducer. A coaxially and confocally aligned PCD was used to record ND emissions. B) B-mode image showing the phase transition of PFP NDs with an initial mean diameter of 400 nm. C) B-mode image of MBs obtained from the phase transition of PFP NDs with a mean diameter of 400 nm. D) B-mode image showing the phase transition of PFP NDs with an initial mean diameter of 200 nm. E) B-mode image of MBs obtained from the phase transition of PFP NDs with a mean diameter of 200 nm.