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The characterization of p18-VLPs. A: Cryo-electron micrograph of frozen-hydrated p18-VLP. B: Reactivity of antibodies HIV447–52D (white bars) and HEV224 (black bars) to the p18-VLPs (non-striated) and WT-VLPs (striated) as determined by ELISA. The data are averaged from triplicate experiments and are expressed as mean ± S.D. Note high immunoreactivity of p18-VLPs with anti-HIV447–52D but it is completely diminished with anti-HEV224.
