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. 2021 Jan 12;12(2):790–801. doi: 10.1364/BOE.403592

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Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.

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Fig. 2. — Illustration of how the SIM frames are generated. The simulated laser illumination varies sinusoidally over time, and so therefore does the average intensity of the ground-truth. The resulting SIM frames are then generated by multiplying the ground-truth frames with the intensity-modulated masks.