Table 2. Functional annotation of TET2 variants.

#CHROM	POS	ID	REF	ALT	Consequence	SIFT	Polyphen2	MutationTaster	CADD phred score
4	1.06E+08	rs12498609	C	G	Non synonymous	D	D	P	23.5
4	1.06E+08	rs111948941	C	T	Non synonymous	D	B	D	22.6
4	1.06E+08	rs749148733	TC	T	Frameshift deletion	.	.	.	32
4	1.06E+08	rs6843141	G	A	Non synonymous	T	B	P	14.05
4	1.06E+08	rs17253672	C	T	Non synonymous	D	P	N	23
4	1.06E+08	.	CA	C	Frameshift deletion	.	.	.	23.8
4	1.06E+08	rs747244398	T	C	Synonymous_SNV	.	.	.	10.13
4	1.06E+08	.	G	T	Stopgain	T	.	D	37
4	1.06E+08	rs111678678	C	T	Non synonymous	D	D	D	23.7
4	1.06E+08	.	A	G	Non synonymous	T	B	N	10.81
4	1.06E+08	.	C	T	Stopgain	D	.	D	40
4	1.06E+08	rs17319679	G	A	ncRNA_intronic	.	.	.	2.046
4	1.06E+08	.	GGT GCC TCC	G	Frameshift deletion	.	.	.	34
4	1.06E+08	rs34402524	T	G	Non synonymous	T	P	P	22
4	1.06E+08	rs2454206	A	G	Non synonymous	T	B	P	0.074
4	1.06E+08	rs62621450	A	G	Non synonymous	T	D	P	22.8
4	1.06E+08	.	G	GGGACAATGACTGTTC CATTGTGTTCTGAGAA AACAAGACCAATGTCA	Frameshift Insertion	.	.	.	25.7