Table 1. Mechanisms and therapeutical concepts of omalizumab in food allergy.
| Effect |
| – Blocks free IgEs |
| – Reduces cell-bound IgEs |
| – Reduces FcεR receptors |
| – Reduces release of mediators |
| Use in the treatment of food allergy |
| – Omalizumab combined with oral immunotherapy |
| – Omalizumab combined with multiple oral immunotherapies |
| – Omalizumab as monotherapy |
| Potential advantages |
| – Reduction in duration of therapy |
| – Better efficacy |
| – Better tolerability at higher doses |
| – Increased tolerance |
| – Reduction of the rate of side effects |