FIG 2.

Determination of the regulons of the XRE-cupin regulators. (A) Volcano plots displaying the RNA-seq results of the genes differentially expressed in the respective XRE-cupin mutants versus parental strain PAO1. Genes for which a DAP-seq binding peak was identified in the promoter are represented by red circles and annotated with their gene ID. The genes (yellow circles) found commonly downregulated in all mutants represent artifacts probably due to genetic manipulation. (B) Summary of number of regulatory targets per TF in P. aeruginosa PAO1.