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. 2021 Feb 22;23(2):e23390. doi: 10.2196/23390

Table 3.

Difference in clinical laboratory indicators (CLIs) between patients with common and severe types of COVID-19.

CLIs Patients with a common type of COVID-19 (n=50) Patients with a severe type of COVID-19 (n=11) P value

n (%) Mean (SD) n (%) Mean (SD)
Procalcitonin (ng/mL) 44 (88) 0.112 (0.170) 11 (100) 0.224 (0.217) .01
N-terminal pro-B-type natriuretic peptide (pg/mL) 29 (58) 366.053 (549.429) 11 (100) 534.782 (398.067) .03
Hypersensitive C-reactive protein (mg/L) 41 (82) 23.332 (34.483) 11 (100) 72.458 (60.805) .002
Lactate dehydrogenase (U/L) 26 (52) 214.896 (73.319) 8 (73) 314.750 (118.755) .02
D-dimer (mg/L) 42 (84) 0.834 (1.115) 11 (100) 5.133 (10.399) .005
Myoglobin (ng/mL) 16 (32) 49.221 (60.505) 7 (64) 103.674 (127.354) .02
Cardiac troponin (ng/mL) 16 (32) 0.011 (0.003) 7 (64) 0.033 (0.041) .02
Creatine kinase (U/L) 27 (54) 81.296 (47.153) 8 (73) 202.125 (195.052) .02
Fibrinogen content (mg/dL) 42 (84) 411.905 (104.363) 11 (100) 467.455 (76.500) .03
Aspartate aminotransferase (U/L) 46 (92) 29.413 (15.756) 10 (91) 45.600 (18.969) .004
γ-glutamyl transpeptidase (U/L) 44 (88) 46.046 (41.609) 10 (91) 80.000 (44.229) .007
Albumin (g/L) 44 (88) 38.602 (6.267) 10 (91) 34.440 (4.558) .02
Albumin to globulin ratio 44 (88) 1.436 (0.507) 10 (91) 1.120 (0.230) .02
Indirect bilirubin (μmol/L) 44 (88) 9.482 (3.841) 10 (91) 7.960 (4.336) .048
Prealbumin (mg/L) 41 (82) 180.171 (83.374) 9 (82) 125.556 (68.182) .03
β2-microglobulin (mg/L) 41 (82) 1.978 (0.430) 9 (82) 2.528 (1.015) .01
Carbon dioxide binding capacity (mmol/L) 41 (82) 25.420 (2.537) 9 (82) 22.733 (2.018) .002
Potassium (mmol/L) 44 (88) 4.057 (0.414) 11 (100) 3.876 (0.251) .04
Erythrocyte sedimentation rate (mm/h) 30 (60) 55.433 (41.639) 7 (64) 87.000 (35.081) .02
Neutrophils (%) 45 (90) 64.496 (13.286) 11 (100) 75.519 (14.001) .02
Lymphocytes (%) 45 (90) 25.711 (10.932) 11 (100) 17.073 (9.750) .01
Eosinophils (%) 45 (90) 1.236 (1.388) 11 (100) 0.391 (1.038) .009
Eosinophil count (×109/L) 45 (90) 0.062 (0.076) 11 (100) 0.014 (0.039) .003
Lymphocyte count (×109/L) 45 (90) 1.255 (0.558) 11 (100) 0.835 (0.383) .008
Packed-cell volume (hematocrit) (L/L) 45 (90) 0.395 (0.050) 11 (100) 0.368 (0.036) .03
Red blood cell distribution width–coefficient of variation (%) 45 (90) 12.658 (1.171) 11 (100) 12.873 (0.781) .03