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. 2021 Feb 22;23(2):e26257. doi: 10.2196/26257

Table 3.

The final scoring model in the development cohort. All values presented in the table represent data collected at the time of initial COVID-19 diagnosis.

Factor Adjusted hazard ratio (95% CI)a P valuea Loge value of hazard ratio Final score
Age (years)

<50 1 (reference) N/Ab 0 0

50-69 6.7 (1.09-43.93) .047 1.831 2

≥70 26.03 (4.26-169.8) <.001 3.186 3
Sex

Female 1 (reference) N/A N/A N/A

Male 1.35 (0.85-2.15) .3 N/A N/A
Comorbidity

Hypertension


No 1 (reference) N/A N/A N/A


Yes 1.21 (.75-1.94) .48 N/A N/A

Diabetes


No 1 (reference) N/A N/A N/A


Yes 1.71 (1.08-2.7) .61 N/A N/A

Dementia


No 1 (reference) N/A 0 0


Yes 3.92 (2.33-6.61) <.001 1.35 1

Chronic cardiac diseasec


No 1 (reference) N/A N/A N/A


Yes 1.15 (.61-2.15) .57 N/A N/A

Cancer in active treatment


No 1 (reference) N/A N/A N/A


Yes 1.83 (.72-4.71) .30 N/A N/A

Chronic pulmonary diseased


No 1 (reference) N/A N/A N/A


Yes 1.76 (.857-3.625) .25 N/A N/A

Chronic renal failure


No 1 (reference) N/A 0 0


Yes 3.48 (1.39-8.85) .045 1.205 1
Symptoms

Dyspnea


No 1 (reference) N/A 0 0


Yes 2.31 (1.44-3.69) .006 .821 1

Fatigue


No 1 (reference) N/A N/A N/A


Yes .69 (.3-1.57) .38 N/A N/A

Mental disturbance


No 1 (reference) N/A 0 0


Yes 4.04 (1.72-9.53) .04 1.268 1
Systolic blood pressure (mmHg)

<140 1 (reference) N/A N/A N/A

≥140 .93 (.57-1.54) .59 N/A N/A
Diastolic blood pressure (mmHg)

<80 1 (reference) N/A N/A N/A

≥80 1.03 (.63-1.68) .63 N/A N/A
Heart rate (per min)

<110 1 (reference) N/A N/A N/A

≥110 1.88 (.96-3.68) .18 N/A N/A
Body temperature (°C)

<38 1 (reference) N/A N/A N/A

≥38 .79 (.39-1.63) .46 N/A N/A
Baseline hemogram

Hemoglobin (g/dL)


≥12.5 1 (reference) N/A N/A N/A


<12.5 1.14 (.71-1.83) .55 N/A N/A

Absolute lymphocyte count (per mm3)


≥1000 1 (reference) N/A 0 0


<1000 2.71 (1.66-4.43) <.001 .982 1

Platelet count (per mm3)


≥100,000 1 (reference) N/A N/A N/A


<100,000 1.68 (.77-3.7) .34 N/A N/A

aBased on 2000 bootstrap samples.

bNot applicable.

cChronic cardiac disease was a composite variable including heart failure and cardiac disease.

dChronic pulmonary disease was a composite variable including asthma and chronic obstructive lung disease.