Table 3.
Factor | Adjusted hazard ratio (95% CI)a | P valuea | Loge value of hazard ratio | Final score | |||||
Age (years) |
|
||||||||
|
<50 | 1 (reference) | N/Ab | 0 | 0 | ||||
|
50-69 | 6.7 (1.09-43.93) | .047 | 1.831 | 2 | ||||
|
≥70 | 26.03 (4.26-169.8) | <.001 | 3.186 | 3 | ||||
Sex | |||||||||
|
Female | 1 (reference) | N/A | N/A | N/A | ||||
|
Male | 1.35 (0.85-2.15) | .3 | N/A | N/A | ||||
Comorbidity | |||||||||
|
Hypertension | ||||||||
|
|
No | 1 (reference) | N/A | N/A | N/A | |||
|
|
Yes | 1.21 (.75-1.94) | .48 | N/A | N/A | |||
|
Diabetes | ||||||||
|
|
No | 1 (reference) | N/A | N/A | N/A | |||
|
|
Yes | 1.71 (1.08-2.7) | .61 | N/A | N/A | |||
|
Dementia | ||||||||
|
|
No | 1 (reference) | N/A | 0 | 0 | |||
|
|
Yes | 3.92 (2.33-6.61) | <.001 | 1.35 | 1 | |||
|
Chronic cardiac diseasec | ||||||||
|
|
No | 1 (reference) | N/A | N/A | N/A | |||
|
|
Yes | 1.15 (.61-2.15) | .57 | N/A | N/A | |||
|
Cancer in active treatment | ||||||||
|
|
No | 1 (reference) | N/A | N/A | N/A | |||
|
|
Yes | 1.83 (.72-4.71) | .30 | N/A | N/A | |||
|
Chronic pulmonary diseased | ||||||||
|
|
No | 1 (reference) | N/A | N/A | N/A | |||
|
|
Yes | 1.76 (.857-3.625) | .25 | N/A | N/A | |||
|
Chronic renal failure | ||||||||
|
|
No | 1 (reference) | N/A | 0 | 0 | |||
|
|
Yes | 3.48 (1.39-8.85) | .045 | 1.205 | 1 | |||
Symptoms |
|
||||||||
|
Dyspnea | ||||||||
|
|
No | 1 (reference) | N/A | 0 | 0 | |||
|
|
Yes | 2.31 (1.44-3.69) | .006 | .821 | 1 | |||
|
Fatigue | ||||||||
|
|
No | 1 (reference) | N/A | N/A | N/A | |||
|
|
Yes | .69 (.3-1.57) | .38 | N/A | N/A | |||
|
Mental disturbance | ||||||||
|
|
No | 1 (reference) | N/A | 0 | 0 | |||
|
|
Yes | 4.04 (1.72-9.53) | .04 | 1.268 | 1 | |||
Systolic blood pressure (mmHg) | |||||||||
|
<140 | 1 (reference) | N/A | N/A | N/A | ||||
|
≥140 | .93 (.57-1.54) | .59 | N/A | N/A | ||||
Diastolic blood pressure (mmHg) | |||||||||
|
<80 | 1 (reference) | N/A | N/A | N/A | ||||
|
≥80 | 1.03 (.63-1.68) | .63 | N/A | N/A | ||||
Heart rate (per min) | |||||||||
|
<110 | 1 (reference) | N/A | N/A | N/A | ||||
|
≥110 | 1.88 (.96-3.68) | .18 | N/A | N/A | ||||
Body temperature (°C) | |||||||||
|
<38 | 1 (reference) | N/A | N/A | N/A | ||||
|
≥38 | .79 (.39-1.63) | .46 | N/A | N/A | ||||
Baseline hemogram | |||||||||
|
Hemoglobin (g/dL) | ||||||||
|
|
≥12.5 | 1 (reference) | N/A | N/A | N/A | |||
|
|
<12.5 | 1.14 (.71-1.83) | .55 | N/A | N/A | |||
|
Absolute lymphocyte count (per mm3) | ||||||||
|
|
≥1000 | 1 (reference) | N/A | 0 | 0 | |||
|
|
<1000 | 2.71 (1.66-4.43) | <.001 | .982 | 1 | |||
|
Platelet count (per mm3) | ||||||||
|
|
≥100,000 | 1 (reference) | N/A | N/A | N/A | |||
|
|
<100,000 | 1.68 (.77-3.7) | .34 | N/A | N/A |
aBased on 2000 bootstrap samples.
bNot applicable.
cChronic cardiac disease was a composite variable including heart failure and cardiac disease.
dChronic pulmonary disease was a composite variable including asthma and chronic obstructive lung disease.