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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Ann Surg. 2020 Sep 1;272(3):427–435. doi: 10.1097/SLA.0000000000004200

Figure 3.

Figure 3.

Patient-derived organoid JHH111 clonal heterogeneity illustrated in fishplot. Notably, the KRAS variant G12R becomes a dominant clone in the culture and is the only clone noted on CLIA testing of the primary tumor.