Table 1.
Demographic, event and injury characteristics for study patients
| Variables | No prophylaxis (n = 898) | Received prophylaxis (n = 3799) | P-value |
|---|---|---|---|
| Age, median (IQR) years | 38.0 (25.0–53.0) | 43.0 (28.0–58.0) | <0.001a |
| Gender | <0.001 | ||
| Male | 611 (68.0%) | 2799 (73.7%) | |
| Female | 287 (32.0%) | 1000 (26.3%) | |
| Primary cause of burn injuryb | <0.001 | ||
| Flame | 345 (38.7%) | 1814 (48.0%) | |
| Scald | 271 (30.4%) | 992 (26.2%) | |
| Contact | 140 (15.7%) | 504 (13.3%) | |
| Other Cause | 136 (15.2%) | 473 (12.5%) | |
| TBSA, median (IQR)c | 2.0 (1.0–4.1) | 4.0 (1.5–9.5) | <0.001a |
| FT TBSA, median (IQR)d,e | 1.0 (0.5–1.5) | 2.0 (1.0–5.0) | <0.001a |
| %TBSA groupc | <0.001 | ||
| 0–9% | 794 (92.8%) | 2817 (75.1%) | |
| 10–19% | 45 (5.3%) | 601 (16.0%) | |
| ≥20% | 17 (2.0%) | 333 (8.9%) | |
| Superficial burnf | <0.001 | ||
| No | 374 (48.3%) | 1930 (56.0%) | |
| Yes | 400 (51.7%) | 1517 (44.0%) | |
| FT burng | <0.001 | ||
| No | 554 (72.9%) | 2099 (60.6%) | |
| Yes | 206 (27.1%) | 1365 (39.4%) | |
| Burn to chest or trunk | <0.001 | ||
| No | 707 (78.7%) | 2664 (70.1%) | |
| Yes | 191 (21.3%) | 1135 (29.9%) | |
| Burn to legs or feet | <0.001 | ||
| No | 532 (59.2%) | 1360 (35.8%) | |
| Yes | 366 (40.8%) | 2439 (64.2%) | |
| Inhalation injuryh | <0.001 | ||
| No | 867 (97.3%) | 3531 (93.4%) | |
| Yes | 24 (2.7%) | 250 (6.6%) | |
| ICU admissioni | <0.001 | ||
| No | 862 (96.1%) | 3264 (85.9%) | |
| Yes | 35 (3.9%) | 534 (14.1%) | |
| ICU LOS, median (IQR) hoursj,k | 30.0 (17.0–62.0) | 72.5 (34.4–264.4) | <0.001a |
| ICD-10-AM codes submitted | <0.001 | ||
| No | 544 (60.6%) | 1745 (45.9%) | |
| Yes | 354 (39.4%) | 2054 (54.1%) | |
| CCI weightl | 0.08 | ||
| 0 | 296 (83.6%) | 1623 (79.0%) | |
| 1 | 43 (12.1%) | 286 (13.9%) | |
| >1 | 15 (4.2%) | 145 (7.1%) |
Data are presented as frequency (percentage) unless otherwise specified. All p values are from a Chi-squared test, unless otherwise specified.
IQR interquartile range, TBSA total body surface area, FT full thickness, ICU intensive care unit, LOS length of stay, ICD-10-AM International Statistical Classification of Diseases and Related Health Problems, 10th Revision, Australian Modification, CCI Charlson Comorbidity Index.
a p values from Mann–Whitney U test
bData missing for 22 patients
cData missing for 90 patients
dFor patients with a full thickness burn
eData missing for 149 patients
fData missing for 476 patients
gData missing for 473 patients
hData missing for 25 patients
iData missing for 2 patients
jFor patients admitted to the ICU
kData missing for 2 patients
lFor patients with ICD-10-AM codes