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. 2021 Feb 3;9:601988. doi: 10.3389/fbioe.2021.601988

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Copyright © 2021 Ul-Islam, Ahmad, Fatima, Shah, Yasir, Ahmad, Manan and Ullah.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytocompatibility analysis of pristine BC and ex situ developed Aloe vera-loaded-BC composite (i.e., BCA). (A) The adhesion and structural morphology of MC3T3-E1 cells on both samples was observed under FE-SEM. (B) The proliferation of MC3T3-E1 cells on the samples was determined by measuring the absorption after 1 and 2 days. The asterisk (^∗) indicates a P-value of <0.05.