FIGURE 1.

Heat stress resistance of C. elegans in the presence of different TCM extracts. C. elegans was treated with seven different TCM plant preparations (30 μg/ml), and DMSO as control, starting at the L4 stage. Heat stress (37 °C for 3 h) was applied at different ages of adulthood (3^rd, 7^th and 12^th day), and the survival after stress was monitored in the different treatment groups (A). The values represent the mean survival ± SEM from three biological replicates. Significant differences were determined by a log-rank test and Bonferroni correction, with *p < 0.05; **p < 0.01; ***p < 0.001 and ****p < 0.0001. In addition, representative survival curves are shown for nematodes treated with E. ulmoides and C. chinensis extracts, which were heat-stressed on the 3^rd (B), 7^th (C) and 12^th (D) day of adulthood.