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. 2021 Feb 3;12:583453. doi: 10.3389/fphys.2021.583453

FIGURE 4.

FIGURE 4

The CCDs of nephrectomy kidney specimens (n = 7) contain an absolute increase in number of cells (A), DBA positive and negative cells (B), and pERK expressing cells (C) than sham (n = 6) controls. The kidneys of mice that received nephrectomy 4 weeks prior to euthanasia contained more cells in the CCD than sham controls (A). A significant increase in DBA negative cells was noted in the nephrectomized mice vs. sham controls (B, ANOVA, #, p < 0.05) while a trend to increased DBA positive cells was observed in nephrectomized mice (@; p = 0.0588). The number of cells that express pERK in the CCD (C) was greater nephrectomy specimens than sham (ANOVA, #, p < 0.05) but no increase in the number of pERK negative cells in CCD of nephrectomy specimens was noted.