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Serum TF-UP level and Alb-UP level as serum biomarkers for acute ischemic stroke, compared with brain tumor-stroke mimics (BT-SM) patients. Receiver operator characteristic (ROC) curve demonstrates sensitivity as a function of 1-specificity to confirm the presence of ischemic stroke by TF-UP/LRP ratio (A) or Alb-UP/LRP ratio (B). TF-UP, transferrin unique peptide; LRP, labeled reference peptide; Alb-UP, albumin unique peptide; AUC, area under the curve.
