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. 2021 Feb 5;12:619310. doi: 10.3389/fneur.2021.619310

Table 2.

Case numbers of patients across categories of serum TF-UP level, stratified by gender, age, diabetes mellitus, hypertension, and previous ischemic heart diseases.

Demographic characteristics No. of patients Serum TF-UP/LRP level P value
I.S. BT-SM Low Medium High
I.S. BT-SM I.S. BT-SM I.S. BT-SM
Overall 94 35 25 0 69 13 0 22 <0.0001
Gender
    Male 56 21 18 0 38 7 0 14 <0.0001
    Female 38 14 7 0 31 6 0 8 <0.0001
Age
    0–29 1 4 0 0 0 1 0 3 0.0504
    30–59 42 25 5 0 37 6 0 19 <0.0001
    60–89 51 6 19 0 32 6 0 0 <0.0671
Diabetes mellitus
    Yes 15 1 4 0 11 1 0 0 0.5510
    No 79 34 21 0 58 12 0 22 <0.0001
Hypertension
    Yes 37 2 9 0 28 2 0 0 0.4265
    No 57 33 16 0 41 11 0 22 <0.0001
Previous IHD
    Yes 13 1 5 0 8 1 0 0 0.4392
    No 81 34 20 0 61 12 0 22 <0.0001

A Cochran-Armitage trend test was used. Results are expressed as percentages or as means (SD); I.S., ischemic stroke; BT-SM, brain tumor-stroke mimics; TF-UP, transferrin unique peptide; LRP, labeled reference peptide; IHD, ischemic heart diseases; Serum TF-UP/LRP level: low, 0– <0.4; medium, 0.4– <0.8; high, 0.8–1.2.