Skip to main content
. 2021 Feb 3;11:642171. doi: 10.3389/fphar.2020.642171

TABLE 1.

Independent variables and responses used in 23 full factorial experimental design for the formulation and optimization of FLV-MEL nano-conjugates.

Independent variables Levels
(−1) (+1)
X1: FLV concentration (mM) 1.00 2.00
X2: MEL concentration (mM) 1.00 5.00
X3: pH 5.50 9.00
Responses Desirability constraints
Y1: particle size (nm) Minimize
Y2: zeta potential (mV) Maximize

Abbreviations: FLV, fluvastatin; MEL, melittin.