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. 2021 Jan 28;8:602707. doi: 10.3389/fcell.2020.602707

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Copyright © 2021 Mao, Li, Hua, Gu, Pan, Chen, Xu, Lu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Increased expression of circPDHX was associated with poor survival in patients with prostate cancer (PCa). (A) Quantitative real-time PCR (qRT-PCR) analysis of the expression levels of circPDHX in PCa and normal tissues (n = 5). (B) Fluorescence in situ hybridization (FISH) analysis of the expression levels of circPDHX in pair-matched PCa tissue samples (n = 75). (C) FISH analysis of the expression levels of circPDHX in PCa tissues with different Gleason scores. (D) Kaplan–Meier analysis of the association of high or low circPDHX expression with overall survival in patients with PCa.