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. 2021 Jan 28;8:602707. doi: 10.3389/fcell.2020.602707

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Copyright © 2021 Mao, Li, Hua, Gu, Pan, Chen, Xu, Lu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Knockdown of circPDHX suppressed PC3 xenograft tumor growth. (A) Representative photographs of the xenograft tumors and assessment of the tumor proliferation trend after treatment with si-circPDHX or si-NC transfected PC3 cells. (B) Comparison of PC3 xenograft tumor volume and weight between si-circPDHX and si-NC groups. (C) Quantitative real-time PCR (qRT-PCR) analysis of circPDHX and miR-378a-3p expression in si-circPDHX or si-NC treated PC3 tumor tissues. (D) Pearson correlation analysis of the correlation of circPDHX with miR-378a-3p expression in si-circPDHX-treated PC3 tumor tissues. Data shown are the mean ± SEM of three experiments. *P < 0.05; **P < 0.01.