Table 1.
Top 10 of upstream analysis associated with DEGs of CD38+CD43+ B cells between healthy donors and SLE.
| Symbol | Entrez Gene Name | *Fold Change | -log10(p-value) | z-score |
|---|---|---|---|---|
| TBX2 | T-Box Transcription Factor 2 | 1.644 | 22.21 | 5.161 |
| E2F3 | E2F Transcription Factor 3 | 1.327 | 17.69 | 4.801 |
| E2F1 | E2F Transcription Factor 1 | 3.332 | 17.52 | 3.907 |
| E2F2 | E2F Transcription Factor 2 | 2.606 | 14.99 | 2.364 |
| MITF | Microphthalmia-associated transcription factor | 1.223 | 11.63 | 5.588 |
| FOXM1 | Forkhead box protein M1 | 4.139 | 11.04 | 5.483 |
| MYOD1 | Myogenic Differentiation 1 | 10.56 | 8.92 | 2.455 |
| STAT1 | signal transducer and activator of transcription 1 | 4.761 | 7.59 | 3.953 |
| IRF7 | interferon regulatory factor 7 | 2.734 | 7.06 | 4.314 |
| IRF1 | interferon regulatory factor 1 | -1.164 | 5.98 | 3.743 |
*Fold Change; CD38+CD43+ of SLE vs CD38+CD43+ of HC.