Table 5.
Kilifi malaria longitudinal cohort (KMLC) cohort microscopic model—predictors of microscopic gametocytemia (adjusted for both AMA1 and gametocyte extract).
| Covariate | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
| Odds ratio | 95% CI | p value | Odds ratio | 95% CI | p value | |
| Age group | ||||||
| <5 years | 1.00 | – | – | 1.00 | – | – |
| 5–9 years | 1.25 | 0.66–2.37 | 0.490 | 0.61 | 0.18–2.06 | 0.427 |
| 10–15 years | 0.95 | 0.39–2.32 | 0.910 | 1.12 | 0.50–2.52 | 0.777 |
| Asexual parasitemia | ||||||
| Negative | 1.00 | – | – | 1.00 | – | – |
| Positive | 5.80 | 2.98–11.28 | <0.001 | 1.26 | 0.51–3.10 | 0.608 |
| AMA1 response | 2.06 | 1.56–2.73 | <0.001 | 1.53 | 0.98–2.42 | 0.062 |
| Gametocyte extract response | 2.69 | 1.78–4.09 | <0.001 | 1.41 | 0.82–2.41 | 0.209 |
| Cohort | ||||||
| Junju | 1.00 | – | – | 1.00 | – | – |
| Ngerenya Early | 2.03 | 0.97–4.28 | 0.061 | 0.99 | 0.84–4.69 | 0.116 |
| Ngerenya Late | 0.13 | 0.05–0.32 | <0.001 | 0.18 | 0.06–0.51 | 0.001 |
*The p-values in bold are statistically significant at level p < 0.05.