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. 2021 Feb 5;8:624339. doi: 10.3389/fcell.2020.624339

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Copyright © 2021 Chen, Liu, Wang, Yu, Zhang, Liu, Chen, Zhu and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein–protein interaction analysis of the differentially expressed proteins using the STRING database. (A) The protein–protein interaction (PPI) maps of the differentially expressed proteins in untreated 3xTg-AD mice vs. WT mice. (B) The PPI maps of the differentially expressed proteins in 1 mg/kg/d DAU-treated 3xTg-AD mice vs. untreated 3xTg-AD mice. (C) The PPI maps of the differentially expressed proteins in 10 mg/kg/d DAU-treated 3xTg-AD mice vs. untreated 3xTg-AD mice. Visualization of PPI maps in Cytoscape 3.7.1 software: green represents downregulation and red represents upregulation.