Table 1.
Major characteristics of patients according to the type of infection.
| Influenza (n = 865) | SARS-CoV-2 n = 872) | p value | |
|---|---|---|---|
| Age (median, IQR) | 69 (51–80) | 67 (53–78) | 0.191 |
| Sex – females (%) | 55.8 | 45.4 | <0.001 |
| BMI (median, IQR) | 26.26 (22.68–30.06) | 27.55 (24.45–24.45) | <0.001 |
| Prior liver disease (%) | 4.4 | 2.8 | 0.087 |
| Cardiovascular diseases | 45.8 | 49.4 | 0.141 |
| In-hospital pneumonia (%) | 17.5 | 64.2 | <0.001 |
| Antibiotic treatment (%) | 67.3 | 50.5 | <0.001 |
| Antiviral treatment (%) | 80.6 | 20.3 | <0.001 |
| Saturation (%)min (median, IQR) | 94.00 (90.00–97.00) | 92.00 (86.00–96.00) | <0.001 |
| Systolic BPmin (median, IQR) | 108.00 (95.00–127.00) | 107.00 (98.00–121.00) | 0.364 |
| Albuminmin (median, IQR) | 3.60(3.20–4.00) | 3.30 (2.80–3.80) | <0.001 |
| Lymphmin (median, IQR) | 0.60 (0.40–1.00) | 0.80 (0.50–1.20) | <0.0001 |
| CRPmax (median, IQR) | 6.22 )2.95–13.98) | 9.10 (2.92–19.36) | <0.001 |
| ALTmax (median, IQR) | 23.00 (16.00–37.50) | 26.20 (17.00–53.00) | <0.001 |
| ASTmax (median, IQR) | 30.00 (22.00–46.00) | 33.05 (22.87–62.65) | <0.001 |
| ALKPmax (median, IQR) | 82.00 (65.00–114.00) | 88.00 (68.00–128.00) | 0.004 |
| GGTmax (median, IQR) | 32.50 (18.00–75.50) | 50.00 (24.00–115.00) | <0.001 |
| ALTmax 40–200 (%) | 20.6 | 32.1 | |
| ALTmax 200–400 (%) | 0.8 | 0.9 | |
| ALTmax >400 (%) | 0.8 | 1.2 | |
| ASTmax 40–200 (%) | 28.6 | 37.0 | |
| ASTmax 200–400 (%) | 2.4 | 3.1 | |
| ASTmax >400 (%) | 0.8 | 1.1 | |
| TBilmax (median, IQR) | 0.45 (0.30–0.70) | 0.50 (0.35–0.80) | <0.0001 |
| INRmax (median, IQR) | 1.09 (0.97–1.26) | 1.15 (1.06–1.30) | <0.001 |
| Death (%) | 6.4 | 15.9 | <0.001 |
| Mechanical ventilation or death (%) | 8.6 | 20.3 | <0.001 |
Variables were compared between groups using the non-parametric Wilcoxon rank-sum test or Chi-square test for independence. ALKP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate transaminase; CRP, C-reactive protein; GGT, gamma-glutamyl transferase; INR, international normalised ratio; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; TBil, total bilirubin.