Table 2.

Effect of cumulative cardiovascular risk factors (RFs) on primary and secondary outcomes

	Cumulative RFs	Model 1			Model 2
		HR	95% CI	P value	HR	95% CI	P value
Mortality	0 RF	1 (ref)			1 (ref)
	1 RF	1.04	0.76 to 1.43	0.786	1.01	0.73 to 1.39	0.956
	≥2 RF	1.52	1.15 to 2.02	0.004	1.38	1.02 to 1.86	0.034
ICU admission	0 RF	1 (ref)			1 (ref)
	1 RF	1.11	0.80 to 1.53	0.534	1.06	0.77 to 1.47	0.723
	≥2 RF	1.15	0.85 to 1.56	0.355	1.07	0.77 to 1.48	0.681
ICU mortality	0 RF	1 (ref)			1 (ref)
	1 RF	0.86	0.46 to 1.60	0.625	1.01	0.73 to 1.39	0.957
	≥2 RF	1.52	0.90 to 2.55	0.115	1.38	1.02 to 1.86	0.035

Cox regression for the effect of cumulative cardiovascular risk factors on mortality, ICU admission and ICU mortality, after adjustment for sex and age (model 1), and with additional adjustments for obesity, smoking and history of coronary artery disease (model 2).

ICU, intensive care unit.