Table 3.

Effect of antihypertensive, lipid-lowering and antidiabetic medications on mortality

Mortality	Model 1			Model 2
	HR	95% CI	P value	HR	95% CI	P value
0 antihypertensive-Rx	1 (ref)			1 (ref)
1 antihypertensive-Rx	1.08	0.81 to 1.43	0.597	1.04	0.78 to 1.38	0.790
≥2 antihypertensive-Rx	1.46	1.11 to 1.91	0.006	1.33	1.01 to 1.76	0.043
0 lipid-lowering-Rx	1 (ref)			1 (ref)
≥1 lipid-lowering-Rx	1.25	0.99 to 1.56	0.058	1.14	0.89 to 1.45	0.292
0 antidiabetic-Rx	1 (ref)			1 (ref)
1 antidiabetic-Rx	1.34	0.97 to 1.85	0.077	1.25	0.9 to 1.74	0.182
≥2 antidiabetic-Rx	2.09	1.55 to 2.80	<0.001	1.93	1.43 to 2.62	<0.001

Cox regression for the effect of the number of antihypertensive, lipid-lowering and antidiabetic drug classes on 21-day mortality, defined as either hospital mortality or discharge for palliative care, with adjustment for age and sex (model 1), and with additional adjustments for obesity, smoking and history of coronary artery disease (model 2).

Rx, medication.;