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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Bioessays. 2020 Nov 6;43(1):e2000202. doi: 10.1002/bies.202000202

Figure 3. A Wnt-mediated transformation of bone marrow stromal cell identity coordinates cortical bone regeneration.

Figure 3.

The quiescent fat precursor-like subset of CXCL12+LepR+ BMSCs can de-differentiate into skeletal stem cell-like cells in response to injury, and re-differentiate into osteoblasts to facilitate bone regeneration, in a manner mediated by canonical Wnt signaling.