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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: J Thromb Haemost. 2020 Nov 27;19(2):536–546. doi: 10.1111/jth.15154

Figure 1. Platelet-specific deficiency of Glut 1 and 3 protects mice from acute ischemic stroke.

Figure 1.

Platelet-specific Glut 1 and 3 deficient (DKO) mice or control mice (WT) were subjected to one-hour tMCAO. (A) Representative brain sections were stained with 2,3,5-triphenyl-tetrazolium chloride. Red areas indicate healthy brain tissue, while white areas show infarcted brain tissue. (B) Quantification of brain infarct volumes 24 hours after stroke. (C) The Bederson test was used to assess neurological outcome 24 hours after stroke. A lower score indicates better neurologic function. (D) To measure motor function, we employed a grip test 24 hours after stroke. A higher score indicates better motor function.