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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Neurobiol Aging. 2020 Dec 15;99:11–18. doi: 10.1016/j.neurobiolaging.2020.12.009

Table 3.

Multimodal imaging and pathologic findings in 13 autopsy cases

Case Clinical diagnosis Pathologic group Sex Age at scan, yrs Scan to death, yrs Core clinical features of DLB DaTQUANT putamen z-score PiB SUVr FDG CIS ratio MRI HP/TIV Lewy related pathology AD neuropathological change Braak
NFT staging
1 DLB LBD M 77 4 3 −4.39 1.31 1.06 0.452 Neocortical (diffuse) Low III
2 DLB LBD M 77 4 3 −2.38 1.65 1.20 0.502 Neocortical (diffuse) Low II
3 DLB LBD M 75 5 4 −3.57 1.53 1.20 0.534 Neocortical (diffuse) Low II
4 DLB LBD M 89 6 4 −4.03 1.34 1.12 0.341 Neocortical (diffuse) Not II
5 DLB LBD M 61 6 4 −4.34 1.17 1.03 0.488 Neocortical (diffuse) Not None
6 DLB LBD M 71 5 2 −4.76 1.33 1.19 0.465 Neocortical (diffuse) Low II
7 DLB LBD M 74 2 3 −2.39 2.22 1.06 0.459 Neocortical (diffuse) Low III
8 DLB LBD + AD M 63 6 3 −2.37 1.59 1.17 0.489 Neocortical (diffuse) Intermediate V
9 DLB LBD + AD M 74 1 2 −3.69 2.07 1.11 0.441 Neocortical (diffuse) Intermediate III
10 ADem LBD + AD F 75 2 0 −4.52 2.42 0.99 0.380 Neocortical (diffuse) High V
11 ADem LBD + AD F 63 3 0 0.78 2.63 0.90 0.487 Neocortical (diffuse) High V
12 ADem AD M 59 3 0 −0.54 2.22 0.77 0.428 None Intermediate IV
13 ADem AD M 74 5 0 0.02 1.86 1.00 0.388 Amygdala-predominant High VI