Table 2.

Examples of Stable Topics, Labels, and Analysis Groups.

Groups	Topic Labels	Top 15 Probable Words
AAV Diagnosis	AAV	anca vasculitis rituximab renal skin prednisone ckd rituxan azathioprine wegener chest steroid chronic clear disease
	Granulomatosis with Polyangiitis	anca wegener prednisone azathioprine rituxan clear granulomatosis normal month hypertension stable skin chest past allergy
	Churg-Strauss Syndrome	churg strauss stenosis asthma anca rituximab recurrent wegener cough syndrome steroid dose cell sputum treat
AAV Treatment	AAV-Specific Treatment	tablet anca rituximab prednisone cyclophosphamide steroid vasculitis positive skin chest start normal clear improve month
	General Treatment*	prednisone anca rheumatology gpa foot symptom rash swell joint vasculitis deny loss rituximab lab chest
	General Treatment*	prednisone swell wegener hand normal joint knee methotrexate esr anca month negative crp vasculitis
Articular, Cutaneous, and Neurologic	Skin Lesion	skin lesion area left rash cream dermatology scalp review include face exam apply cell discuss
Symptoms	Foot Ulcer	grant foot mcg lesion pyoderma premphase dpm refer left toe start gangrenosum ultram normal ditropan
	Joint Issues	left knee hip shoulder joint fracture spine ankle hand foot physical lumbar swell motion mild
	Neurology Evaluation	left normal head intact neurology weakness stroke headache brain nerve seizure exam hand sensation gait
Head and Neck	Head and Neck	sinus nasal ear left hear nose symptom normal
Involvement in AAV	Manifestations	sinusitis strep throat wegener granulomatosis rash pneumo
Pulmonary Involvement in AAV	Pulmonary Findings	chest left lobe lung nodule upper lower find pleural pulmonary small effusion impression opacity pneumonia
	Pulmonary Symptoms	pulmonary lung cough disease chest prednisone anca oxygen dyspnea fev interstitial fvc mild ild increase
	Bronchiectasis*	bronchiectasis culture hemoptysis specimen sputum name† chest neg neb negative lobe pneumonia pulmonary stable result
	Bronchiectasis*	bronchiectasis neg pseudomonas sputum flare oral nasal mucoid chest neb hyperlipidemia inhaler disease sen stable smear
Kidney Involvement in AAV	Glomerulonephritis*	renal negative anca urine positive antibody anti igg vasculitis result cell normal protein disease hematuria
	Glomerulonephritis*	renal anca vasculitis prednisone cytoxan anemia disease steroid failure creatinine cyclophosphamide admission dose start rpgn
	End Stage Renal Disease	renal esrd fistula transplant left disease folic acid buhle unit catheter nephrocaps access stage hemodialysis
	Renal Transplant	transplant renal tacrolimus prograf donor post cellcept mycophenolate disease bid immunosuppression cmv negative risk rejection
Psychiatric disorders	Psychiatric Disorders	disorder anxiety problem mood depression report support feel axis assessment cocaine current deny think treatment
Complications of AAV	Infections	culture fever negative specimen antibiotic infection sputum infectious result blood admission vancomycin gram report cough
	Diabetes	unit insulin diabetes give blood lantus sugar dose time nph mellitus scale strip meal slide

^*Topics with the same labels were merged for trend analysis

^†a limitation of the name lexicon is that it does not remove all names; Abbreviations: AAV: antineutrophil cytoplasm antibody-associated vasculitides; anca: antineutrophil cytoplasm antibody; mcg: microgram, gpa: granulomatosis with polyangiitis, esr: erythrocyte sedimentation rate, crp: C-reactive protein, neb: nebulizer, fvc: forced vital capacity, fev: forced expiratory volume, mmhg: millimeters mercury, igg: Immunoglobulin-G, rpgn: rapidly progressive glomerulonephritis, esrd: end stage renal disease, cmv: cytomegalovirus, dvt: deep vein thrombosis, ckd: chronic kidney disease