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. 2021 Feb 10;15:610078. doi: 10.3389/fnbeh.2021.610078

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Copyright © 2021 Bernaud, Hiroi, Poisson, Castaneda, Kirshner, Gibbs and Bimonte-Nelson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Study timeline and WRAM configurations. (A) The study timeline depicts the age at arrival and the commencement of behavioral testing, including WRAM and VP. (B) The 8-Arm WRAM apparatus, with seven of the eight arms platformed. Besides the starting arm, all other arms in the 8-Arm WRAM are spatial working memory arms. (C) The 12-Arm WRAM apparatus, with seven of the 12 arms platformed, making for a total of seven working memory arms, like that of the 8-Arm WRAM. This maze, however, has five reference memory arms, allowing for the analysis of both spatial reference and working memory performance on the WRAM.