Table 3.
Ancestry | z (p Value) | Hazard ratios [95% CI] comparing percentiles of PHS2 | |||
---|---|---|---|---|---|
HR20/50: ≤20th vs. 30–70th | HR80/50: ≥80th vs. 30-70th | HR98/50: ≥98th vs. 30–70th | HR80/20: ≥80th vs. ≤20th | ||
All (n = 78,221) | 15.9 (p = 6.3 × 10−57) | 0.43 [0.41–0.56] | 2.47 [2.33–2.64] | 4.46 [4.04–4.98] | 5.68 [5.07–6.46] |
Hazard ratios (HRs) from Cox proportional hazards models are shown comparing men in the highest 2% of genetic risk (≥98th percentile of PHS), highest 20% of genetic risk (≥80th percentile), average risk (30–70th percentile), and lowest 20% of genetic risk (≤20th percentile). p Values reported are two-tailed from the Cox models.