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. 2021 Feb 23;12:1236. doi: 10.1038/s41467-021-21287-0

Table 3.

Association of PHS with death from prostate cancer.

Ancestry z (p Value) Hazard ratios [95% CI] comparing percentiles of PHS2
HR20/50: ≤20th vs. 30–70th HR80/50: ≥80th vs. 30-70th HR98/50: ≥98th vs. 30–70th HR80/20: ≥80th vs. ≤20th
All (n = 78,221) 15.9 (p = 6.3 × 10−57) 0.43 [0.41–0.56] 2.47 [2.33–2.64] 4.46 [4.04–4.98] 5.68 [5.07–6.46]

Hazard ratios (HRs) from Cox proportional hazards models are shown comparing men in the highest 2% of genetic risk (≥98th percentile of PHS), highest 20% of genetic risk (≥80th percentile), average risk (30–70th percentile), and lowest 20% of genetic risk (≤20th percentile). p Values reported are two-tailed from the Cox models.