Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 24;6:77. doi: 10.1038/s41392-020-00456-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — BBR stimulated the production of dopamine in striatum in mice transplanted with E. faecalis or E. faecium: TMP-TFB-derivatized MALDI-MS images. a The relative abundance and distributions of dopamine with a spatial resolution of 200 µm. b Rescaled image from a with baseline subtraction and total ion count normalization. c The relative abundance and distributions of dopamine with a spatial resolution of 100 µm. d The relative abundance and distributions of dopamine in half brains from the same mice in c with a spatial resolution of 200 µm. All of them showed elevated levels of dopamine after BBR addition. (group 1: normal group; group 2: antibiotic treated only; group 3: antibiotics and E. faecalis; group 4: antibiotics, E. faecalis, and BBR (200 mg/kg); group 5: antibiotics, E. faecium; and group 6: antibiotics, E. faecium, and BBR (200 mg/kg)). Blue represents the decreased level and red represents the increased level. The striatal dopamine level in the mice receiving both E. faecalis and BBR was higher than that treated with E. faecalis only (group 3 vs. group 4). The striatal dopamine in the mice receiving both E. faecium and BBR was higher than that treated with E. faecium only (group 5 vs. group 6)