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. 2021 Feb 23;11:4343. doi: 10.1038/s41598-021-83827-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Left: Five examples of plugins (from top to bottom): The image filter plugin allows to make common intensity adjustments to the image, the annotation plugin shows the available annotations and their frequency of use. The search field allows to query the database for arbitrary annotation properties. The media plugin can be used to play media files attached to an annotation. The EIPH-Score plugin is an example of a domain-specific plugin, allowing to calculate the Doucet score¹⁰. Right: A screenshot of the annotation view depicting a WSI with polygon annotations, the list of images in the image set and the screening mode plugin, which enables the user to screen the image persistently. The screening plugin visualise the screened area in green and a purple rectangle for the current field of view.