Table 4.
HCV selected domains | |||
---|---|---|---|
Antigen | Position | Amino-acid sequence | Importance |
CORE | 16_30 | NRRPQDVKFPGGGQI | 0.023 |
21_35 | DVKFPGGGQIVGGVY | 0.074 | |
26_40 | GGGQIVGGVYLLPRR | 0.165 | |
31_45 | VGGVYLLPRRGPRLG | 0.118 | |
36_50 | LLPRRGPRLGVRATR | 0.058 | |
41_55 | GPRLGVRATRKTSER | 0.015 | |
61_75 | RRQPIPKARQPEGRA | 0.020 | |
66_80 | PKARQPEGRAWAQPG | 0.013 | |
76_90 | WAQPGYPWPLYGNEG | 0.054 | |
101_115 | RGSRPSWGPTDPRRR | 0.013 | |
E2 | 1_20 | ETHVTGGNAGRTTAGLVGLL | 0.064 |
76_95 | CRRLTDFAQGWGPISYANGS | 0.005 | |
86_105 | WGPISYANGSGLDERPYCWH | 0.015 | |
121_140 | GPVYCFTPSPVVVGTTDRSG | 0.007 | |
131_150 | VVVGTTDRSGAPTYSWGAND | 0.029 | |
181_200 | CGAPPCVIGGVGNNTLLCPT | 0.002 | |
191_210 | VGNNTLLCPTDCFRKHPEAT | 0.010 | |
201_220 | DCFRKHPEATYSRCGSGPWI | 0.014 | |
216_235 | SGPWITPRCMVDYPYRLWHY | 0.007 | |
226_245 | VDYPYRLWHYPCTINYTIFK | 0.007 | |
NS5 | 121_170 | VTRVGDFHYVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLR | 0.014 |
261_310 | WRQEMGGNITRVESENKVVILDSFEPLQAEEDEREVSVPAEILRRSRKFP | 0.045 | |
271_320 | RVESENKVVILDSFEPLQAEEDEREVSVPAEILRRSRKFPRAMPIWARPD | 0.035 | |
281_330 | LDSFEPLQAEEDEREVSVPAEILRRSRKFPRAMPIWARPDYNPPLLESWK | 0.068 | |
291_340 | EDEREVSVPAEILRRSRKFPRAMPIWARPDYNPPLLESWKDPDYVPPVVH | 0.019 | |
311_360 | RAMPIWARPDYNPPLLESWKDPDYVPPVVHGCPLPPAKAPPIPPPRRKRT | 0.046 | |
371_420 | ALAELATKTFGSSESSAVDSGTATASPDQPSDDGDAGSDVESYSSMPPLE | 0.008 | |
381_430 | GSSESSAVDSGTATASPDQPSDDGDAGSDVESYSSMPPLEGEPGDPDLSD | 0.012 | |
391_440 | GTATASPDQPSDDGDAGSDVESYSSMPPLEGEPGDPDLSDGSWSTVSEEA | 0.016 | |
NS3 | 29_96 | QVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLT | 0.008 |
81_130 | QDLVGWQAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSP | 0.006 | |
391_440 | AYYRGLDVSVIPTSGDVIVVATDALMTGFTGDFDSVIDCNTCVTQTVDFS | 0.011 |