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. 2021 Feb 10;11:619896. doi: 10.3389/fimmu.2020.619896

Table 4.

HCV selected domains and the corresponding importance score.

HCV selected domains
Antigen Position Amino-acid sequence Importance
CORE 16_30 NRRPQDVKFPGGGQI 0.023
21_35 DVKFPGGGQIVGGVY 0.074
26_40 GGGQIVGGVYLLPRR 0.165
31_45 VGGVYLLPRRGPRLG 0.118
36_50 LLPRRGPRLGVRATR 0.058
41_55 GPRLGVRATRKTSER 0.015
61_75 RRQPIPKARQPEGRA 0.020
66_80 PKARQPEGRAWAQPG 0.013
76_90 WAQPGYPWPLYGNEG 0.054
101_115 RGSRPSWGPTDPRRR 0.013
E2 1_20 ETHVTGGNAGRTTAGLVGLL 0.064
76_95 CRRLTDFAQGWGPISYANGS 0.005
86_105 WGPISYANGSGLDERPYCWH 0.015
121_140 GPVYCFTPSPVVVGTTDRSG 0.007
131_150 VVVGTTDRSGAPTYSWGAND 0.029
181_200 CGAPPCVIGGVGNNTLLCPT 0.002
191_210 VGNNTLLCPTDCFRKHPEAT 0.010
201_220 DCFRKHPEATYSRCGSGPWI 0.014
216_235 SGPWITPRCMVDYPYRLWHY 0.007
226_245 VDYPYRLWHYPCTINYTIFK 0.007
NS5 121_170 VTRVGDFHYVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLR 0.014
261_310 WRQEMGGNITRVESENKVVILDSFEPLQAEEDEREVSVPAEILRRSRKFP 0.045
271_320 RVESENKVVILDSFEPLQAEEDEREVSVPAEILRRSRKFPRAMPIWARPD 0.035
281_330 LDSFEPLQAEEDEREVSVPAEILRRSRKFPRAMPIWARPDYNPPLLESWK 0.068
291_340 EDEREVSVPAEILRRSRKFPRAMPIWARPDYNPPLLESWKDPDYVPPVVH 0.019
311_360 RAMPIWARPDYNPPLLESWKDPDYVPPVVHGCPLPPAKAPPIPPPRRKRT 0.046
371_420 ALAELATKTFGSSESSAVDSGTATASPDQPSDDGDAGSDVESYSSMPPLE 0.008
381_430 GSSESSAVDSGTATASPDQPSDDGDAGSDVESYSSMPPLEGEPGDPDLSD 0.012
391_440 GTATASPDQPSDDGDAGSDVESYSSMPPLEGEPGDPDLSDGSWSTVSEEA 0.016
NS3 29_96 QVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLT 0.008
81_130 QDLVGWQAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSP 0.006
391_440 AYYRGLDVSVIPTSGDVIVVATDALMTGFTGDFDSVIDCNTCVTQTVDFS 0.011