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. 2021 Feb 10;12:624097. doi: 10.3389/fphys.2021.624097

FIGURE 2.

FIGURE 2

Hypothetical example of continuous and discrete latent biological states measured with three proxy biomarkers. Color represents the latent continuous state, and circles vs. triangles represent the discrete state. The proxy biomarkers x and y but not z are associated with the continuous state, and the proxy biomarkers y and z but not x are associated with the discrete state.