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. 2021 Feb 10;12:633047. doi: 10.3389/fmicb.2021.633047

FIGURE 1.

FIGURE 1

A schematic representation of IL-1 family receptors, co-receptors, and ligands. Each ligand, receptor and co-receptor are separated into their appropriate IL-1 subfamily. An arrow indicates the induction of signaling; a flat line indicates the blocking of signaling. The latest nomenclature is used, for previous/alternative nomenclature see Table 1.