Table 1.
Clinical characteristics with comparison of normotensive pregnant women and women with pre-eclampsia.
| Characteristics | Preeclamptic N = 65 |
Normotensive N = 60 |
p-value |
|---|---|---|---|
| Age, years | 31 ± 5 | 29 ± 6 | 0.060 |
| Caucasian* | 27 (51%) | 27 (60%) | 0.370 |
| Body Mass Index, kg/m2 | 27 ± 6 | 25 ± 7 | 0.100 |
| Systolic BP, mmHg | 154 ± 20 | 117 ± 14 | < 0.010 |
| Diastolic BP, mmHg | 96 ± 11 | 68 ± 11 | < 0.010 |
| Proteinuria, g/24 h | 1.50 [0.57–4.43] | N.D | – |
| Platelet count, × 109/L | 148 ± 84 | 234 ± 55 | < 0.010 |
| Lactate dehydrogenase | 300 [239–551] | 176 [136–213] | < 0.010 |
| Nifedipine retard | 27 (42%) | 9 (15%) | 0.000 |
| Magnesiumsulphate | 23 (35%) | 0 | 0.000 |
| Nulliparous† | 35 (57%) | 34 (58%) | 0.980 |
| Gestational age at delivery, weeks + days | 33 + 5 ± 3 + 6 | 34 + 1 ± 3 + 6 | 0.470 |
| Birth weight, grams | 1914 ± 832 | 2292 ± 876 | 0.020 |
| Birth weight percentile* | 4.9 ± 1.6 | 6.2 ± 2.6 | 0.005 |
| Soluble syndecan-1 (ng/ml) | 553 [309–805] | 550 [307–920] | 0.957 |
Numbers represent mean ± standard deviation, median with [interquartile range], or number of subjects with percentages. †Data missing for 4 women with pre-eclampsia and 1 normotensive woman. *Data on birth weight percentile missing for 18 women with pre-eclampsia and for 8 normotensive women. Between group differences were assessed by t-test for parametric, Mann–Whitney U test for non-parametric distributions and Chi square test for nominal variables. p-values were considered to indicate a significant difference if p < 0.05.