TABLE 2.

Summary of peripheral blood plasma cytokine concentrations in children with ASD and healthy controls.

	Plasma concentration (mean ± SD, pg/ml)		p-value	Q-value1
	ASD (n = 45)	Control (n = 41)
IL-1β	2.30 ± 0.65	2.15 ± 0.93	0.136	0.212 NS
IL-2	31.23 ± 44.32	3.58 ± 1.88	<0.0001	< 0.0001****
IL-4	8.88 ± 7.04	5.26 ± 4.19	0.00723	0.0145*
IL-5	3.92 ± 2.14	2.71 ± 1.30	0.0179	0.0312*
IL-6	20.54 ± 18.74	5.54 ± 4.06	0.000137	0.000638***
IL-8	12.75 ± 5.32	13.23 ± 4.97	0.562	0.562 NS
IL-10	9.64 ± 5.06	6.04 ± 2.73	0.000309	0.00108**
IL-12 p70	6.39 ± 2.16	5.70 ± 0.71	0.332	0.423 NS
IL-17A	4.75 ± 4.44	4.33 ± 2.12	0.525	0.562 NS
IL-17F	4.72 ± 1.71	4.58 ± 2.08	0.529	0.562 NS
IL-22	1.13 ± 0.64	1.03 ± 0.84	0.263	0.368 NS
TNF-α	6.92 ± 5.65	3.91 ± 1.63	0.00295	0.00689**
TNF-β	4.50 ± 1.46	3.05 ± 1.01	<0.0001	0.000189***
IFN-γ	5.96 ± 3.49	3.50 ± 0.60	0.00112	0.00314**

¹NS: non-significant at an FDR-adjusted p-value (Q-value) cutoff of 0.05; *Q < 0.05, **Q < 0.01, ***Q < 0.001, ****Q < 0.0001.