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Ras GTP hydrolysis site. (A) Key residues responsible for the active conformation in the pre-catalytic state for GTP-hydrolysis in H-Ras (PDB ID 3K8Y). Pivotal inter-residue distance distributions reflecting K-Ras4B GTP-hydrolysis capability, (B) from Q61 Cα atom to GTP Pγ atom, (C) from Q61 OE1 atom to GTP Pγ atom and (D) from Y32/pY32 side chain OH atom to GTP Pγ atom.
